DNA自组装与信息存储

DNA self-assembly and information storage

脱氧核糖核酸(Deoxyribonucleic acid,DNA)作为未来数据的存储介质具有巨大的潜力.近年来,DNA自组装技术发展迅速,其中DNA折纸(origami)和DNA瓦片(tile)设计及组装技术已经实现了纳米结构的原子级精度.DNA自组装纳米结构因其具有空间可寻址性、可编程性等优点,为基于DNA自组装的信息存储提供了发展平台.文章综述了基于DNA自组装技术的两种组装模型及DNA信息存储领域的发展现状,总结了当前基于DNA单链、DNA origami和DNA tile的信息存储,概述了当前基于DNA的信息存储领域中面临的挑战,并展望了DNA自组装及其在信息存储领域的应用前景.

Deoxyribonucleic acid(DNA)has great potential as a storage container for future data.In recent years,DNA self-assembly technology has developed rapidly,including DNA origami and DNA tile techniques which have achieved on atomic-level precision for assembly.DNA self-assembled nanostructures provide a development platform for DNA-based information storage due to their spatial addressability and editing.This paper reviews two assembly models based on DNA self-assembly technology and the development status of DNA information storage,summarizes the current information storage based on single-stranded DNA,DNA origami,and DNA tile techniques.At last,the paper outlines the current challenges in the field of DNA-based information storage and the prospects of DNA self-assembly technology in the field of information storage.