结肠灌洗辅助Ⅰ期切除吻合术治疗急性结肠梗阻患者的效果分析

Analysis of the Effect of Colonoscopy Assisted Stage I Resection and Anastomosis in the Treatment of Acute Colonic Obstruction

目的:探讨结肠灌洗辅助Ⅰ期切除吻合术治疗急性结肠梗阻患者的临床效果。方法:选取2016年1月—2018年12月我科收治的急性肠梗阻患者60例,随机分为对照组(Ⅰ期切除吻合术,30例)与观察组(结肠灌洗辅助Ⅰ期切除吻合术,30例)。比较两组患者手术时间、首次肛门排气时间、住院时间,Karnofsky体力状况(KPS)评分,肿瘤坏死因子α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)水平,术后并发症发生情况。结果:两组患者手术时间、首次肛门排气时间无明显差异(P>0.05),观察组患者住院时间短于对照组(P<0.05);观察组患者KPS评分优良率高于对照组(P<0.05);观察组患者TNF-α、IL-6、CRP水平低于对照组(P<0.05);观察组患者术后并发症发生率低于对照组(P<0.05)。结论:结肠灌洗辅助Ⅰ期切除吻合术治疗急性结肠梗阻患者可缩短手术时间、促进病情恢复,改善术后生活质量及炎性反应,降低术后并发症的发生。

Objective:To investigate the clinical effect of Coloclysis assisted stage I resection and anastomosis in the treatment of acute colonic obstruction.Methods:60 patients with acute intestinal obstruction admitted to our department from January 2016 to December 2018 were randomly divided into control group(stage I resection and anastomosis,30 cases)and observation group(30 patients with colon lavage assisted stage I resection and anastomosis).The postoperative complications were compared with the two groups:operation time,first anal exhaust time,hospitalization time,Karnofsky physical condition(KPS),tumor necrosis factorα(tnf-α),interleukin-6(IL-6),C reactive protein(CRP).Results:There was no significant difference in the operation time and the first anal exhaust time between the two groups(P>0.05),the hospitalization time of the observation group was shorter than that of the control group(P<0.05);the excellent rate of KPS score in the observation group was higher than that of the control group(P<0.05);the tnf-α,IL-6 and CRP levels of the observation group were lower than that of the control group(P<0.05);the postoperative complications of the observation group were lower than that of the control group(P<0.05).Conclusion:Colonoscopy assisted stage I resection and anastomosis can shorten the operation time,promote the recovery of the disease,improve the quality of life and inflammatory response after operation,and reduce the occurrence of postoperative complications.