归肺理气方加减治疗慢性阻塞性肺疾病急性加重期痰热壅肺证疗效观察

Effect of Guifei Liqi Prescription on The Treatment of Phlegm Heat Type in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的探究归肺理气方加减对慢性阻塞性肺疾病急性加重期痰热壅肺证临床疗效。方法将60例慢阻肺急性加重期痰热壅肺证患者随机分为对照组和治疗组,对照组用西医常规治疗,治疗组在西医常规治疗基础上加用归肺理气方加减治疗。结果治疗后治疗组总有效率(96.7%)高于对照组(86.7%,P<0.05);两组治疗后血清炎症指标WBC、CRP及IL-6与治疗前相比均有改善;且治疗组各项指标优于对照组(P<0.05)。结论归肺理气方加减联合西医常规治疗能有效降低WBC、CRP和IL-6血清炎症指标,改善肺功能,缓解慢阻肺急性加重期痰热壅肺证患者的临床症状,提高疗效。

Objective To explore the clinical effect of Guifei Liqi Decoction on acute exacerbation of chronic obstructive pulmonary disease.Methods 60 patients with acute exacerbation of chronic obstructive pulmonary disease with phlegm heat obstructing lung syndrome were randomly divided into control group and treatment group.The control group was treated with conventional western medicine,while the treatment group was treated with Guifei Liqi Decoction on the basis of conventional western medicine.Results After treatment,the total effective rate of the treatment group(96.7%)was higher than that of the control group(86.7%,P<0.05);After treatment,WBC,CRP and IL 6 were improved in both groups;The indexes of the treatment group were better than those of the control group(P<0.05).Conclusion Guifei Liqi decoction combined with conventional western medicine can effectively reduce WBC,CRP and IL 6 serum inflammatory indexes,improve lung function,relieve the clinical symptoms of patients with acute exacerbation of chronic obstructive pulmonary disease with phlegm heat obstructing lung syndrome,and improve the curative effect.