摘要
目的:分析1例成人腺病毒重症肺炎伴呼吸衰竭患者抗感染治疗用药的合理性。方法:对收治的1例成人腺病毒重症肺炎伴呼吸衰竭患者,经抗菌药物阶梯治疗、抗病毒及免疫调节治疗,分析其抗感染用药的全过程,并评估了其临床疗效与用药的合理性。结果:腺病毒导致重症肺炎合并I型呼吸衰竭患者的病情进展迅速,采用多种抗菌药物及免疫调节剂联用治疗后治愈出院,疗效较为明显。结论:重症肺炎患者在抗感染治疗的同时,应辅以免疫调节治疗,提高了临床疗效。
Objective:To analyze the rationality of anti-infective medication in a case of adult severe adenovirus pneumonia with respiratory failure.Methods:A case of adult severe adenovirus pneumonia with respiratory failure was treated with antibacterial de-escalation therapy,antiviral therapy and immunomodulatory therapy.The whole process of anti-infective medication was analyzed,and the clinical efficacy and rationality of medication was evaluated.Results:Severe pneumonia with type I respiratory failure caused by adenovirus developed rapidly and was cured and discharged after combined treatment with a variety of antibacterials and immunomodulators with obvious curative effect.Conclusion:Immune regulation therapy should be supplemented with anti-infection therapy in patients with severe pneumonia,which could improve the clinical efficacy.
作者
万君
吴凤
胡琪
崔洁
伍三兰
帅诗媛
黄怡菲
WAN Jun;WU Feng;HU Qi;CUI Jie;WU San-lan;SHUAI Shi-yuan;HUANG Yi-fei(Department of Pharmacy,Gezhouba Central Hospital of Sinopharm,The No.3 Clinical Medical College,China Three Gorges University,Yichang Hubei 443002,China;Union Hospital of Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430022,China)
出处
《抗感染药学》
2021年第5期665-671,共7页
Anti-infection Pharmacy
关键词
腺病毒
重症肺炎
抗感染药物
免疫调节
用药分析
adenovirus
severe pneumonia
anti-infective drugs
immune regulation
drug analysis