呼吸气体传感器在肺癌早期诊断中的研究进展

Research progress of breath gas sensor in early diagnosisof lung cancer

从传感器对肺癌标志物挥发性有机物的灵敏度和选择性等方面,综述了几种肺癌早期筛查和诊断用传感器的研究现状和发展前景。指出提高传感器在痕量气体中的灵敏度、保证传感器在室温条件下正常工作以及在相对湿度环境的选择性仍然是接下来的研究重点,同时需要加大针对不同发病进程肺癌患者呼吸气体的检测,建立有机物的浓度与肿瘤发病进程关系模型,为临床筛查和诊断工作提供理论基础。

From the sensitivity and selectivity of sensors to volatile organic compounds,several sensors for early diagnosis of lung cancer are reviewed.Improving sensitivity in trace gases,the operation at room temperature and the selectivity in relative humidity environment are still research focus is pointed out.Meanwhile,it is necessary to increase the detection of breath gases in patients with different degrees of lung cancer,and establish the relationship model between the concentration of volatile organic compounds and tumor progression,which provides theoretical basis for clinical diagnosis.