中药汤剂联合药物贴敷对小儿支原体肺炎的临床疗效和免疫功能的影响

The effect of TCM decoction plus external application on mycoplasma pneumonia in children and immune function

目的:分析中医汤剂联合药物贴敷对小儿支原体肺炎的临床效果及对免疫功能的影响。方法:选取泸州市古蔺县中医医院收治的支原体肺炎患儿80例作为观察对象,选取时间为2018年10月-2020年1月,并将其按照随机法进行平均分组,其中接受常规西药进行治疗的40例纳入参照组,接受中药汤剂联合药物贴敷进行治疗的40例纳入试验组,分析这两组患儿的症状体征消失时间、住院时间、治疗前后的细胞免疫功能以及不良反应发生率。结果:从症状、体征消失时间上看,试验组患儿的退热时间、咳嗽消失时间以及肺部湿啰音消失时间均短于参照组,对比差异明显(P<0.05);试验组患儿的住院时间也明显短于参照组,差异显著(P<0.05);从细胞免疫功能指标上看,治疗前,试验组患儿的T淋巴细胞亚群(CD4^(+)、CD8^(+))以及CD4^(+)/CD8^(+)与参照组相比,差异无统计学意义(P>0.05),而治疗后,试验组患儿的各项细胞免疫功能指标均优于参照组,对比差异显著(P<0.05);从不良反应发生率上看,两组的差异无统计学意义(P>0.05)。结论:对支原体肺炎患儿采取中药汤剂联合药物贴敷进行治疗具有较高的临床应用价值,值得推广。

Objective:To analyze the clinical effect of TCM decoction plus external application on mycoplasma pneumonia in children and its influence on immune function.Methods:80 cases were divided into groups according to randomization.40 cases that received conventional Western medicine were included in the reference group,and 40 cases that received TCM decoction plus external application were included in the experimental group.Results:The antipyretic time,cough disappearance time and lung moist rales disappearance time in the experimental group were shorter than those in the reference group,(P<0.05).The hospital stay length in the experimental group was also significantly shorter than the reference group(P<0.05).After treatment,the various cellular immune function indexes in the experimental group were better than the reference group(P<0.05).The difference between the groups in the incidence of adverse reaction was not statistically significant(P>0.05).Conclusion:TCM decoction plus external application on mycoplasma pneumonia in children shows high clinical value,and is worthy of promotion.