上海市青浦区社区居民代谢综合征流行现状及影响因素分析

A survey about epidemiological situation and influencing factors of metabolic syndrome among community residents in Qingpu District,Shanghai

目的了解上海市青浦区35岁及以上社区居民代谢综合征流行特征及主要影响因素,为科学防控提供参考依据。方法于2017年6月,通过多阶段分层抽样对青浦区11个街镇5029名35岁及以上社区居民开展成人慢病危险因素问卷调查和健康体检,使用Logistic多因素逐步回归模型计算相关性和危险度,分析其影响因素。结果青浦区35岁以上成人代谢综合征患病率为32.40%,女性代谢综合征患病率为38.40%,高于男性的26.60%;年龄组中≥75岁的代谢综合征患病率最高,为44.36%;文化程度以不识字/少识字组代谢综合征患病率较高,为44.65%;不吸烟者代谢综合征患病率高于吸烟者,为33.85%,以上差异均有统计学意义(P<0.05)。多因素Logistic回归结果显示,以35~44年龄组为参考,随着年龄的增加,患病率上升;女性相对于男性代谢综合征患病率高,OR值为1.984(95%CI:1.723~2.302);高超敏C反应蛋白居民相对于正常超敏C反应蛋白居民代谢综合征患病率高,OR值为2.241(95%CI:1.872~2.691);高同型半胱氨酸居民相对于正常同型半胱氨酸居民代谢综合征患病率高,OR值为1.454(95%CI:1.284~1.641)。结论青浦区35岁以上社区居民代谢综合征流行情况较为严重,加强早期筛查和干预,是降低代谢综合征不良结局发生率、减轻疾病负担、提高健康水平的有效措施。

Objective To understand the epidemic characteristics and main influencing factors of metabolic syndrome among community residents aged 35 and over in Qingpu District,Shanghai,provide reference basis for scientific prevention and control.Methods In June 2017,through multi-stage stratified sampling,5029 community residents aged 35 and over in 11 Street towns of Qingpu District were investigated by questionnaire and physical examination.The correlation and risk were calculated by logistic stepwise regression model,and the influencing factors were analyzed.Results The prevalence of metabolic syndrome in adults over 35 years old in Qingpu District was 32.40%,and the prevalence of metabolic syndrome in women was 38.40%,which was higher than 26.60%in men;In the age group,the prevalence of metabolic syndrome≥75 years old was the highest,which was 44.36%;The prevalence of metabolic syndrome was higher in illiterate/less literate group,which was 44.65%;The prevalence of metabolic syndrome in nonsmokers was 33.85%higher than that in smokers(P<0.05).The results of multivariate logistic regression showed that the prevalence increased with the increase of age;The prevalence of metabolic syndrome in women was higher than that in men,and the OR value was 1.984(95%CI:1.723-2.302);The prevalence of metabolic syndrome in residents with hypersensitive C-reactive protein was higher than that in residents with normal hypersensitive C-reactive protein and the OR value was 2.241(95%CI:1.872-2.691);The prevalence of metabolic syndrome in high homocysteine residents is higher than that in normal homocysteine residents,the OR value was 1.454(95%CI:1.284-1.641).Conclusion The prevalence of metabolic syndrome in community residents over 35 years old in Qingpu District is serious.Strengthening early screening and intervention is to reduce the incidence of adverse outcomes of metabolic syndrome and reduce the disease burden,Effective measures to improve health level.