中西医结合治疗糖尿病神经源性膀胱的疗效分析

Analysis on effect of combination of traditional Chinese and western medicine in treating diabetic neurogenic bladder

目的比较不同中西医结合方法治疗糖尿病神经源性膀胱(DNB)的疗效。方法选取重庆市南岸区中西医结合医院2019年10月至2020年10月收治的DNB患者150例,采用随机数字表法分为3组,各50例。A组给予甲钴胺治疗,B组给予甲钴胺+补中益气汤加减治疗,C组给予甲钴胺+补中益气汤加减+针灸理疗治疗。比较治疗周期结束后各组膀胱残余尿、下尿路症状量表(BLUTS-SF)评分。结果B组1例患者脱失,C组1例患者因不配合退出试验。治疗后,3组膀胱残余尿、BLUTS-SF评分均较治疗前明显降低(P<0.05);A、B、C组复合达标率分别为10.00%、57.14%、77.55%,A组<B组<C组,组间两两比较差异均有统计学意义(P<0.01)。结论甲钴胺+补中益气汤加减+针灸短期治疗DNB临床疗效好,复合达标率较高。

Objective To compare the efficacies of different methods of integrated traditional Chinese and western medicine in the treatment of diabetic neurogenic bladder(DNB).Methods One hundred and fifty patients with DNB treated in Nanan District Hospital of Integrated Traditional Chinese and Western Medicine from October 2019 to October 2020 were selected and divided into three groups by adopting the random number table method,50 cases in each group.Group A was given the mecobalamin treatment,group B was treated with mecobalamin plus Buzhong Yiqi Decoction add and subtract treatment,and group C was given mecobalamin plus Buzhong Yiqi Decoction add and subtract plus acupuncture and physiotherapy.The bladder residual urine and score of the lower urinary tract symptoms scale(Bristol Lower Urinary Tract Symptoms-Short Form,BLUTS-SF)at the end of treatment cycle were compared among the groups.Results One case in group B was taken off and one case in group C dropped out of the trial due to imparity.After treatment,the residual urine and BLUTS-SF scores in 3 groups were significantly decreased compared with before treatment(P<0.05);the compound reaching standard rates of group A,B and C were 10.00%,57.14%and 77.55%,respectively,group A<group B<group C,and the intergroup pairwise comparison had statistically significant difference(P<0.01).Conclusion Mecobalamin plus Buzhong Yiqi decoction add and subtract plus acupuncture has good effective in the short-term treatment of DNB with high compound reaching standard rate.