添加益生菌治疗对48例超高龄人群胃肠动力障碍疗效研究

Effect of probiotic treatment on gastrointestinal motility disorders in 48 cases of ultra-elderly population

目的:探究超高龄人群胃肠动力障碍治疗中添加益生菌治疗的临床效果。方法:选择96例超高龄胃肠动力障碍患者依据治疗方法不同分为对照组和观察组各48例。对照组实施肠内营养治疗,观察组添加益生菌治疗。比较两组患者临床疗效及营养生化水平情况。结果:观察组治疗有效率显著高于对照组(87.5%vs 62.5%,P<0.05);观察组白蛋白、前白蛋白和转铁蛋白分别是(43.2±11.3)g/L、(232.5±40.2)μg/mL和(322.1±50.3)ng/mL均明显高于对照组的(40.1±10.6)g/L、(192.2±40.4)μg/mL和(274.7±50.8)ng/mL(P<0.05)。结论:相比于常规肠内营养治疗,添加益生菌治疗能够有效改善患者胃肠功能,提高营养生化水平,综合治疗效果更显著。

Objective:To explore the clinical effect of probiotics in the treatment of gastrointestinal dyskinesia in the elderly.Methods:Ninty-six patients with gastrointestinal dyskinesia were divided into control group(48 cases)and observation group(48 cases).The control group was treated with enteral nutrition and the observation group was treated with probiotics.The clinical curative effect and the level of nutrition and biochemistry were compared between the two groups.Results:The effective rate of the observation group was significantly higher than that of the control group(87.5%vs 62.5%,P<0.05).Albumin,prealbumin and transferrin(43.2±11.3)g/L,(232.5±40.2)μg/mL and(322.1±50.3)ng/mL in the observation group were significantly higher than those in the control group(40.1±10.6)g/L,(192.2±40.4)μg/mL and(274.7±50.8)ng/mL(P<0.05),respectively.Conclusion:Compared with routine enteral nutrition therapy,probiotic therapy can effectively improve gastrointestinal function and biochemical level of nutrition,and the comprehensive treatment is more effective.