摘要
Dear Editor,Short tandem repeats(STRs),polymorphic DNA regions with a variable number of repeated units(2–6 base pairs),are attractive to forensic applications such as human identification and parentage testing[1].Nowadays,most of the commercial STR kits are designed based on STRs from the combined DNA index system(CODIS),European Standard Set(ESS),expanded CODIS,and extended ESS[2].In this study,we evaluated 21 STRs from GoldeneyeTM DNA ID 22NC kit(PeopleSpot Inc.,Beijing,China),which including 20 polymorphic non-CODIS STR loci(i.e.D1S1656,D2S441,D3S1744,D3S3045,D4S2366,D5S2500,D6S477,D7S1517,D7S3048,D8S1132,D10S1248,D10S1435,D11S2368,D13S325,D14S608,D15S659,D17S1290,D18S535,D19S253,D22GATA198B05)and a CODIS STR locus(D3S1358),in five ethnic groups(i.e.Eastern Han,Ningxia Hui,Xinjiang Uygur,Xizang Tibetan,and Inner Mongolia Mongolian)of China.The forensic genetic investigation of above loci may provide more genetic information in complex kinship testing and population studies[3,4].
基金
supported by the National Key R&D Program of China[grant number 2016YFC0800703]
the National Natural Science Fund for Distinguished Young Scholars[grant number 81625013]
the Standard Program of Shanghai Municipality[grant number 16DZ0501600]
the Public Interest Research Grant Program of National Research Institutes[grant number GY2017D-2]
General Program of National Natural Science Foundation of China.