全身麻醉复合硬膜外麻醉对胃癌根治术患者肺功能的影响研究

The effect of general anesthesia combined with epidural anesthesia on lung function of patients who undergoing radical surgery for gastric cancer

目的:探讨全身麻醉复合硬膜外麻醉在胃癌根治术中的临床应用价值。方法:2018年1月-2020年2月收治实施胃癌根治术的患者57例,随机分为两组。研究组采用全身麻醉复合硬膜外麻醉;对照组实施全身麻醉。比较两组临床效果。结果:研究组术后3d的MVV-ME/FEV1、MVV/FEV1水平均高于对照组,RV/TLC水平低于对照组,差异有统计学意义(P<0.05);研究组自主呼吸恢复时间、睁眼时间和拔管时间均低于对照组,差异有统计学意义(P<0.05);研究组肺部感染率低于对照组,差异有统计学意义(P<0.05)。结论:对胃癌根治术患者实施全身麻醉复合硬膜外麻醉,相对于单纯的全身麻醉,能够更好减轻麻醉对患者肺功能的影响,降低肺部感染率,为患者的术后康复打下坚实基础。

Objective:To explore the clinical value of general anesthesia combined with epidural anesthesia on lung function of patients who undergoing radical surgery for gastric cancer.Methods:From January 2018 to February 2020,57 cases of patients who underwent radical surgery for gastric cancer were enrolled,they were randomly divided into two groups.The study group used general anesthesia combined with epidural anesthesia.The control group underwent general anesthesia.The effects between the two groups was compared.Results:The MVV-ME/FEV1 and MVV/FEV1 levels of the study group were higher than those of the control group at 3 days after operation,the RV/TLC level was lower than the control group,the differences were statistically significant(P<0.05).The spontaneous breathing recovery time,eye opening time and extubation time of the study group were all lower than those of the control group,the differences were statistically significant(P<0.05).The lung infection rate in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Compared with general anesthesia alone,general anesthesia combined with epidural anesthesia can better reduce the effect of anesthesia on lung function of patients,reduce pulmonary function infection,and lay a solid foundation for postoperative rehabilitation of patients.