“三圣方”治疗宫颈人乳头瘤病毒持续感染合并糜烂样改变临床观察

Clinical observation of"Sanshengfang"in the treatment of cervical HPV persistent infection with erosive changes

目的:观察自拟中药“三圣方”膏治疗宫颈人乳头瘤病毒(HPV)持续感染合并糜烂样改变的临床疗效。方法:2015年6月-2017年8月收治宫颈HPV持续感染合并糜烂样改变患者232例,随机分为两组。试验组给予“三圣方”膏宫颈局部涂药治疗;对照组给予保妇康栓紧贴宫颈放置治疗。比较两组临床疗效。结果:试验组HPV临床改善率及糜烂样改变的治疗总有效率均明显高于对照组,差异有统计学意义(P<0.05)。结论:自拟中药“三圣方”膏宫颈局部涂药,可使HPV转阴,同时又使宫颈糜烂样改变转光滑,疗效确切。

Objective:To observe the clinical efficacy of self-made traditional Chinese medicine"Sanshengfang"ointment in the treatment of persistent infection of cervical human papilloma(HPV)with erosive changes.Methods:From June 2015 to August 2017,232 patients with cervical HPV persistent infection and erosive changes were selected and randomly divided into two groups.The experimental group was treated with"Sanshengfang"ointment.The control group was treated with Baofukang Suppository close to the cervix.We compared the clinical efficacy of the two groups.Results:In the experimental group,the clinical improvement rate of HPV and the total effective rate of erosive changes were significantly higher than those in the control group,the difference was statistically significant(P<0.05).Conclusion:The self-made traditional Chinese medicine"Sanshengfang"ointment can make HPV negative and cervical erosion smooth at the same time,the curative effect is definite.