颅内小型动脉瘤破裂危险因素分析

Risk factors for rupture of small intracranial aneurysm

目的探讨颅内小型动脉瘤破裂的危险因素。方法回顾分析235例颅内小型动脉瘤患者的病例资料,根据动脉瘤是否破裂分为破裂组(n=177)与未破裂组(n=58)。对2组患者的临床资料及瘤体特征进行单因素分析,运用Logistic回归模型分析颅内小型动脉瘤破裂的独立危险因素。结果 2组高血压病史、吸烟史、饮酒史、动脉瘤部位以及动脉瘤形态等指标比较,差异有统计学意义(P <0.05)。高血压病史、饮酒史、吸烟史、动脉瘤部位以及动脉瘤形态均是颅内小动脉瘤破裂的影响因素。结论颅内小型动脉瘤的破裂与患者高血压病史、饮酒史、吸烟史、动脉瘤部位、动脉瘤形态密切相关。

Objective To investigate the risk factors for rupture of small intracranial aneurysms.Methods The clinical data of 235 patients with small intracranial aneurysm was retrospectively analyzed and divided into ruptured group(n=177)and unruptured group(n=58)according to whether aneurysm ruptured or not.The clinical data and tumor characteristics of the two groups were analyzed by univariate analysis,and the independent risk factors for small intracranial aneurysm rupture were analyzed by Logistic regression model.Results There were significant differences in hypertension history,smoking history,drinking history,aneurysm location and aneurysm shape between the two groups(P<0.05).History of hypertension,history of drinking alcohol,smoking,aneurysm location and shape are influencing factors for rupture of small intracranial aneurysm.Conclusion Rupture of small intracranial aneurysm is closely related to the history of hypertension,drinking history,smoking history,aneurysm location and irregular shape of aneurysm.