MECT联用氟西汀治疗抑郁症诱发癫痫1例

MECT combined with fluoxetine in the treatment of depression-induced seizures:A case report

无抽搐电休克治疗(MECT)是当前治疗重型精神疾病的有效手段,其安全性高,推荐治疗于众多难治性精神疾病如抑郁症、精神分裂症等,同时会出现不明原因且较为少见的不良反应。本例为抑郁症患者使用MECT治疗间歇期突发失神、抽搐、口吐白沫,及时予以抗癫痫治疗及后续辅助检查,诊断为癫痫大发作,属较为罕见的不良反应。本文通过文献复习结合本病例总结MECT治疗间歇期出现癫痫发作可能的危险因素,对早期预防不良反应的发生具有重要意义。

Modified electroconvulsive therapy(MECT)is an effective method for severe mental diseases with high safety and is recommended to treat many refractory mental diseases such as refractory depression and schizophrenia,but there are also unexplained and less common adverse reactions.This case was diagnosed as grand mal seizure by antiepileptic therapy and follow-up examination.It was a rare adverse reaction after patients with depression were treated with MECT.In this paper,we reviewed the literature and summarized the possible risk factors of epileptic seizures during the intermittent period of MECT,and understood the adverse effects of MECT,which is of great significance to reduce the occurrence and prognosis of the side effects after MECT,and to provide the basis for early prevention.