上消化道黏膜病变病理诊断结果分析

Analysis of Pathological Diagnosis Results of Upper Gastrointestinal Mucosal Lesions

目的观察上消化道黏膜病变病理诊断结果。方法方便选择2017年1月—2020年6月在该院接受诊治的上消化道黏膜病变患者90例,观察幽门螺杆菌感染情况与上消化道肿瘤、溃疡、息肉、胃炎的关系。结果胃炎病变女性HP阳性率100.0%显著高于男性(72.7%),差异有统计学意义(χ^(2)=4.625,P=0.031);20~45岁年龄段HP阳性率(100.0%)显著高于46~81岁年龄段(50.0%),差异有统计学意义(χ^(2)=11.304,P<0.001);上消化道黏膜息肉女性HP阳性发病率(100.0%)显著高于男性(33.3%),差异有统计学意义(χ^(2)=18.462,P<0.001);20~45岁年龄段HP阳性发病率(100.0%)显著高于46~81岁年龄段(50.0%),差异有统计学意义(χ^(2)=12.692,P<0.001);上消化道黏膜溃疡男性HP阳性发病率(100.0%)显著高于女性(50.0%),差异有统计学意义(χ^(2)=5.455,P=0.020);46~81岁年龄段HP阳性发病率(100.0%)显著高于20~45岁年龄段,差异有统计学意义(χ^(2)=12.000,P<0.001);上消化道黏膜恶性肿瘤男性HP阳性发病率(100.0%)显著高于女性(25.0%),差异有统计学意义(χ^(2)=15.632,P<0.001);46~81岁年龄段HP阳性发病率(100.0%)显著高于20~45岁年龄段(40.0%),差异有统计学意义(χ^(2)=11.811,P<0.001)。结论上消化道黏膜溃疡的发生与感染幽门螺杆菌密切相关,慢性胃炎、上消化道黏膜息肉的高发群体为青中年女性,肿瘤与溃疡的高发群体为中老年男性。

Objective To observe the pathological diagnosis results of upper gastrointestinal mucosal lesions.Methods 90 patients with upper gastrointestinal mucosal lesions who were diagnosed and treated in the hospital from January 2017 to June 2020 were convenient selected to observe the relationship between Helicobacter pylori infection and upper gastrointestinal tumors,ulcers,polyps,and gastritis.Results The HP positive rate of 100.0%in women with gastritis lesions was significantly higher than 72.7%in men,and the difference was statistically significant(χ^(2)=4.625,P=0.031);the HP positive rate of 100.0%in the 20-45 age group was significantly higher than that in the 46-81 age group of 50.0%,the difference was statistically significant(χ^(2)=11.304,P<0.001);the HP-positive incidence rate of upper gastrointestinal mucosal polyps in women of 100.0%was significantly higher than that of men 33.3%,and the difference is statistically significant(χ^(2)=18.462,P<0.001);The incidence of HP positive in the age group of 20 to 45 years old was 100.0%significantly higher than that of 50.0%in the age group of 46 to 81 years old,the difference was statistically significant(χ^(2)=12.692,P<0.001);HP positive in men with upper gastrointestinal mucosal ulcer incidence rate of 100.0%was significantly higher than that of female 50.0%,and the difference was statistically significant(χ^(2)=5.455,P=0.020);the HP-positive incidence rate of 100.0%in the 46-81 year-old age group was significantly higher than that in the 20-45 year-old age group,and the difference was statistically significant(χ^(2)=12.000,P<0.001);the HP-positive incidence rate of upper gastrointestinal mucosal malignant tumors in males,100.0%,was significantly higher than that in females,25.0%,and the difference was statistically significant(χ^(2)=15.632,P<0.001);The incidence of HP-positive in the 46-81-year-old age group of 100.0%was significantly higher than that of 40.0%in the 20-45-year-old age group,and the difference was statistically significant(χ^(2)=11.811,P<0.001).Conclusion The occurrence of upper gastrointestinal mucosal ulcers is closely related to Helicobacter pylori infection.The high incidence of chronic gastritis and upper gastrointestinal mucosal polyps are young and middle-aged women,and the high incidence of tumors and ulcers is middle-aged and elderly men.