鼻肠管肠内营养支持对重症创伤性脑损伤患者营养指标及并发症的影响

Effects of naso-intestinal tube enteral nutrition support on nutritional indexes and complications in patients with severe traumatic brain injury

目的分析鼻肠管肠内营养支持对重症创伤性脑损伤患者营养指标及并发症的影响。方法选取2018年3月至2020年3月我院收治的200例重症创伤性脑损伤患者作为研究对象,根据治疗方法将其分为对照组与观察组,各100例。对照组给予鼻胃管肠内营养支持,观察组给予鼻肠管肠内营养支持。比较两组患者的营养指标、血清炎症因子水平、临床指标及并发症发生情况。结果治疗后,两组的Hb、Alb、PAB水平均升高,且观察组高于对照组(P<0.05)。治疗后,两组的IL-1β、hs-CRP水平均降低,且观察组低于对照组(P<0.05)。观察组的ICU入住时间、达到肠内营养目标量时间均短于对照组(P<0.05)。观察组的并发症总发生率低于对照组(P<0.05)。结论鼻肠管肠内营养支持能够改善重症创伤性脑损伤患者的营养状况,抑制炎性反应,减少并发症的发生,促进病情恢复。

Objective To analyze the effects of naso-intestinal tube enteral nutrition support on nutritional indexes and complications in patients with severe traumatic brain injury.Methods A total of 200 patients with severe traumatic brain injury admitted in our hospital from March 2018 to March 2020 were selected as the research objects,and the patients were divided into control group and observation group according to the treatment methods,with 100 cases in each group.The control group was given nasogastric tube enteral nutrition support,and the observation group was given naso-intestinal tube enteral nutrition support.The nutritional indexes,serum inflammatory factors levels,clinical indexes and complications were compared between the two groups.Results After treatment,the levels of Hb,Alb and PAB in the two groups increased,and those in the observation group were higher than the control group(P<0.05).After treatment,the levels of IL-1βand hs-CRP in the two groups decreased,and those in the observation group were lower than the control group(P<0.05).The ICU stay time and the time to reach the target amount of enteral nutrition in the observation group were shorter than those in the control group(P<0.05).The total incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion Naso-intestinal tube enteral nutrition support can improve the nutritional status,inhibit inflammatory response,reduce complications and promote the recovery of the disease of patients with severe traumatic brain injury.