慢性肾脏病合并肌少症干预措施的研究进展

Research progress of intervention measures in chronic kidney disease complicated with sarcopenia

研究表明,肌少症可导致临床不良事件的发生,包括降低生活质量、增高住院率和病死率。与一般人群相比,慢性肾脏病患者肌少症的患病率明显升高,这与慢性肾脏病复杂的发病机制密切相关。本文对慢性肾脏病患者合并肌少症的流行病学、病因、发病机制和干预措施研究进展进行综述,旨在为慢性肾脏病患者肌少症的治疗和预防提供参考。

Studies have shown that sarcopenia can result in adverse clinical outcomes,including reduced quality of life and increased hospitalization and mortality rates.Compared with the general population,the prevalence of sarcopenia in patients with chronic kidney disease is significantly higher.This phenomenon is closely related to the complicated pathogenesis of the chronic kidney disease.In this review,we mainly discuss the epidemeology,etiology,pathogenesis and interventions of sarcopenia in patients with chronic kidney disease to provide reference for the treatment and prevention of sarcopenia in patients with chronic kidney disease.