腹腔镜袖状胃切除术治疗肥胖症及其合并症的研究进展

Research progress of laparoscopic sleeve gastrectomy in treatment of obesity and its comorbidities

目的探究腹腔镜袖状胃切除术(LSG)对肥胖症及其合并症的治疗效果。方法收集国内外LSG治疗肥胖症及其合并症相关研究的文献并进行综述。结果 LSG不但可以有效地减轻肥胖症患者的体质量,而且对肥胖症相关的合并症如2型糖尿病、阻塞性睡眠呼吸暂停综合征、多囊卵巢综合征、原发性高血压、高脂血症等也有明显的缓解作用。结论 LSG的长期减重效果确切有效且与其他常见减重术式的减重效果相当,因其还具有操作简单、安全、高效、合并症较少等特点而被更多的患者和临床医师所认可,近年来得到快速发展,但在某些合并症如胃食管反流病方面的治疗效果存在较大争议,仍需要进一步去研究明确。

Objective To explore the effect of laparoscopic sleeve gastrectomy(LSG)on obesity and its comorbidities.Method The literatures about LSG in the treatment of obesity and its comorbidities were collected and summarized.Results LSG could not only effectively reduce the weight of patients with obesity,but also obviously alleviate comorbidities related to obesity,such as type 2 diabetes mellitus,obstructive sleep apnea syndrome,polycystic ovary syndrome,essential hypertension,hyperlipidemia,and so on.Conclusions LSG has a definite and effective long-term weight loss effect,which is equal to other common weight loss methods.It has been recognized by more and more patients and clinicians because it has advantages of simple operation,safety,high efficiency and fewer complications.However,therapeutic effects of some comorbidities,such as gastroesophageal reflux disease,are still controversial and need further to be studied.