男性飞行员高尿酸血症影响因素分析

Analysis of hyperuricemia and its risk factors in male pilots

目的分析男性飞行员高尿酸血症患病情况及其危险因素。方法采用方便抽样方法,选择1561名男性飞行员为研究对象,以其中678例罹患高尿酸血症者为观察组,883名无罹患高尿酸血症者为对照组,比较2组人群高尿酸血症患病情况。结果男性飞行员高尿酸血症患病率为43.4%。观察组人群体质量指数(BMI)偏高、三酰甘油(TG)偏高、高密度脂蛋白胆固醇偏低、低密度脂蛋白胆固醇(LDL-C)偏高、混合型高脂血症、非酒精性脂肪肝(NAFLD)检出率均高于对照组(P值均<0.01)。多因素Logistic回归分析结果显示,BMI偏高、TG偏高、LDL-C偏高和NAFLD均是男性飞行员罹患高尿酸血症的危险因素(比值比分别为1.517、1.559、1.384、1.782,P值均<0.05),年龄>40岁是其罹患高尿酸血症的保护因素(比值比为0.593,P<0.01)。结论男性飞行员高尿酸血症的患病率较高,须加强飞行员高尿酸血症的防治工作。

Objective To analyze the prevalence and risk factors of hyperuricemia in male pilots.Methods By using the convenient sampling method,1561 male pilots were selected as the study subjects.Among them,678 patients with hyperuricemia were taken as the observation group,and 883 pilots without hyperuricemia were taken as the control group.The incidence of hyperuricemia in the two groups was compared.Results The prevalence of hyperuricemia in male pilots was 43.4%(678/1561).The pilots in the observation group had higher body mass index(BMI),higher triglyceride(TG),lower high-density lipoprotein cholesterol,higher low-density lipoprotein cholesterol(LDL-C),higher mixed hyperlipidemia and higher non-alcoholic fatty liver disease(NAFLD)(all P<0.05)compared with the control group.The result of multivariate logistic regression analysis showed that high BMI,high TG,high LDL-C and NAFLD were the risk factors for hyperuricemia in male pilots(odds ratios were 1.517,1.559,1.384 and 1.782,respectively,all P<0.01),while age≥40 was a protective factor for hyperuricemia(odds ratio was 0.593,P<0.01).Conclusion The prevalence of hyperuricemia in male pilots is relatively high.The prevention and treatment of hyperuricemia in pilots should be strengthened.