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乳酸、DD二聚体与重症颅脑损伤预后的相关性 被引量:3

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摘要 目的分析不同预后患者乳酸、血红蛋白(Hb)及D-二聚体的水平及其与重症颅脑损伤患者预后的相关性。方法选择2019年1月至2020年12月期间兰溪市人民医院收治的重症颅脑损伤患者作为研究对象,利用倾向性评分匹配法消除年龄、性别、受伤类型、致伤原因等混杂因素,获得一般资料平衡的预后良好组及预后不良组患者各41例。比较2组患者病初乳酸、Hb及D-二聚体水平,并分析三者与GOS预后评分的相关性。结果2组患者年龄、性别、受伤至入院时间、入院时GCS评分、受伤类型、致伤原因、血肿位置、脑疝、中线位移及手术情况等一般资料差异无统计学意义(P>0.05)。预后不良的重型颅脑外伤患者乳酸及D-二聚体水平明显高于预后良好组,Hb水平显著低于预后良好组,差异有统计学意义(t=6.68,t=3.76,t=2.10,P<0.05)。Pearson相关性分析结果显示,乳酸及D-二聚体水平与患者预后GOS评分水平呈负相关(r=-0.64,r=-0.31),Hb水平与GOS评分呈正相关(r=0.38)。结论不同预后组重症颅脑损伤患者乳酸、Hb及D-二聚体水平不同,乳酸、Hb及D-二聚体水平与患者预后GOS评分具有显著相关性,是判断预后的重要生化指标。
出处 《浙江创伤外科》 2021年第4期679-681,共3页 Zhejiang Journal of Traumatic Surgery
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