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SARS-CoV-2:A critical review of its history,pathogenesis,transmission,diagnosis and treatment 被引量：1

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摘要 The outbreak of the deadly virus(novel coronavirus or Severe Acute Respiratory Syndrome Coronavirus-2)that emerged in December 2019,remained a controversial subject of intense speculations regarding its origin,became a worldwide health problemresulting in serious coronavirus disease 2019(acronym COVID-19).The concern regarding this new viral strain“Severe Acute Respiratory Syndrome Coronavirus-2”(acronym SARS-CoV-2)and diseases it causes(COVID-19)is well deserved at all levels.The incidence of COVID-19 infection and infectious patients are increasing at a high rate.Coronaviruses(CoVs),enclosed positive-sense RNA viruses,are distinguished by club-like spikes extending from their surface,an exceptionally large genome of RNA,and a special mechanism for replication.Coronaviruses are associated with a broad variety of human and other animal diseases spanning fromenteritis in cattle and pigs and upper chicken respiratory disease to extremely lethal human respiratory infections.With World Health Organization(WHO)declaring COVID-19 as pandemic,we deemed it necessary to provide a detailed review of coronaviruses discussing their history,current situation,coronavirus classification,pathogenesis,structure,mode of action,diagnosis and treatment,the effect of environmental factors,risk reduction and guidelines to understand the virus and develop ways to control it.
作者 Mohd Sharjeel Sofi Aadil Hamid Sami Ullah Bhat
机构地区 Department of Environmental Science
出处 《Biosafety and Health》 2020年第4期217-225,共9页 生物安全与健康（英文）
关键词 CORONAVIRUSES RNA viruses SARS-CoV-2 COVID-19 Biocidal agents
分类号 R563.1 [医药卫生—呼吸系统]
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Biosafety and Health
2020年 第4期

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