溃疡性结肠炎患者生存质量与应对方式、心理状态的关系及其影响因素分析

Relationship Among Quality of Life and Coping Style,Mental State of Patients with Ulcerative Colitis and Its Influencing Factors

目的:探讨溃疡性结肠炎(UC)患者生存质量与应对方式、心理状态的关系,并分析生存质量的影响因素。方法:选取2018年4月~2020年8月期间我院收治的183例UC患者。采用中文版医学应对问卷(MCMQ)评估患者对疾病的应对方式。采用炎症性肠病生存质量问卷(IBDQ)对患者生存质量进行评价。采用焦虑自评症状表(SAS)、抑郁自评症状表(SDS)评估患者心理状态。Pearson相关性分析UC患者生存质量与应对方式、心理状态的关系,应用单因素及多因素Logistic回归分析生存质量的影响因素。结果:UC患者全身症状、肠道症状、社会能力、情感能力、IBDQ总分均低于国内常模(P<0.05)。UC患者SAS、SDS评分均高于国内常模(P<0.05)。UC患者回避、屈服评分均高于国内常模,面对评分低于国内常模(P<0.05)。Pearson相关性分析结果显示:IBDQ总分与SAS、SDS以及回避、屈服评分均呈负相关,与面对评分呈正相关(P<0.05)。单因素分析结果显示:UC患者的生存质量与病情严重程度、婚姻状况、饮酒史、文化程度、性别、家族史、吸烟史、饮食习惯、家庭月均收入、肠道手术史有关(P<0.05)。多因素Logistic回归分析结果显示:病情严重程度为重度、性别女、有家族史、有吸烟史、不良饮食习惯、家庭月均收入≤5000元均是影响UC患者生存质量的危险因素(P<0.05)。结论:UC患者生存质量下降,其生存质量与应对方式、心理状态有关,且受到性别、家族史、病情严重程度等多种因素影响,临床可考虑针对上述影响因素进行相关防治,以改善UC患者生存质量。

Objective:To explore the relationship between quality of life and coping style,mental state in patients with ulcerative colitis(UC),and to analyze the influencing factors of quality of life.Methods:183 patients with UC in our hospital from April 2018 to August 2020 were selected.Chinese version of Medical Coping Questionnaire(MCMQ)was used to evaluate the coping style of patients.The quality of life of patients with inflammatory bowel disease(IBDQ)was evaluated.Self rating Anxiety Scale(SAS)and self rating Depression Scale(SDS)were used to evaluate the mental state of the patients.Pearson correlation analysis was used to analyze the relationship between quality of life and coping style,mental state of patients with UC.Univariate and multivariate logistic regression analysis was used to analyze the influencing factors of quality of life.Results:The general symptoms,intestinal symptoms,social ability,emotional ability and IBDQ total score of patients with UC were lower than those in the domestic norm(P<0.05).The SAS and SDS scores of patients with UC were higher than those in the domestic norm(P<0.05).The avoidance and yield scores of patients with UC were higher than those in the domestic norm,while the face score was lower than that in the domestic norm(P<0.05).Pearson correlation analysis showed that IBDQ total score was negatively correlated with SAS,SDS,avoidance and yield scores,and positively correlated with face score(P<0.05).Univariate analysis showed that the quality of life of patients with UC was related to the severity of illness,marital status,drinking history,education level,gender,family history,smoking history,eating habits,average monthly household income and intestinal surgery history(P<0.05).Multivariate logistic regression analysis showed that severity of the disease was severe,gender female,with family history,with smoking history,bad eating habits,average monthly household income≤5000 yuan were risk factors affecting the quality of life of patients with UC(P<0.05).Conclusion:The quality of life of patients with UC decreased,the uality of life is related to coping style and mental state,and is affected by multiple factors such as gender,family history,severity of illness,etc.Clinically,it can be considered to carry out related prevention and treatment for the above influencing factors to improve the quality of life of patients with UC.