肠道微生态与肿瘤的诊断和治疗

Application of gut microbiome in the diagnosis and treatment of tumor

肠道微生态与人类健康密切相关。肠道微生物组成特征改变促进肿瘤发生发展。特定肠道微生物及其代谢产物调节宿主生理功能和肿瘤微环境,显著影响抗肿瘤治疗反应及其不良反应。靶向肠道微生态的策略在肿瘤诊治中显示出有希望的应用前景。

Gut microbiome is closely related to human health.Changes in intestinal microbial composition promote the development of tumors.Specific intestinal microorganisms and their metabolites regulate host physiological functions and tumor microenvironment,significantly affecting the anti-cancer treatment response and its adverse events.Strategies targeting gut microbiome have shown promising prospects in diagnosis and treatment of cancer.