佛山地区非淋菌性尿道炎男性患者生殖支原体和沙眼衣原体感染情况分析

Analysis of Mycoplasma genitalium and Chlamydia trachomatis infection in male patients with non-gonococcal urethritis in Foshan area

目的探讨佛山地区非淋菌性尿道炎(NGU)男性感染生殖支原体(Mg)和沙眼衣原体(CT)的情况。方法选取2016年1月—2019年3月就诊于佛山市南海区人民医院泌尿外科、皮肤科和男性专科的602例NGU的患者作为病例组,选取2016年1月—2019年3月于佛山市南海区人民医院体检中心查体的200例健康体检者作为对照组。运用SAT-RNA检测技术对佛山地区男性NGU患者和健康体检者的泌尿道分泌物进行Mg和CT核酸检测。比较两组的Mg和CT感染率情况,同时比较病例组患者各年龄段的Mg和CT感染率,分析Mg、CT感染与男性NGU的关系。结果病例组的Mg和CT检出率均高于对照组,差异有统计学意义(P<0.05)。>30~40岁组的Mg、CT感染率最高。不同年龄段患者的Mg和CT感染分布比较,差异无统计学意义(P>0.05)。经Pearson相关性分析,生殖道Mg、CT感染与男性NGU呈正相关性(r=0.14、0.16,P<0.05)。结论男性NGU与Mg、CT的感染相关,临床医生应引起重视,Mg和CT作为泌尿道感染的常规检查项目之一,对发现男性NGU有重要的临床意义。

Objective To analyze the Mycoplasma genitalium(Mg)and Chlamydia trachomatis(CT)infection in male patients with non-gonococcal urethritis(NGU)in Foshan area.Methods A total of 602 patients with non-gonococcal urethritis who were admitted to the Department of Urology,Department of Dermatology and Male Specialist Department of Nanhai District People′s Hospital of Foshan City from January 2016 to March 2019 were selected as the case group.A total of 200 healthy subjects who underwent physical examinations in the Physical Examination Center of Nanhai District People′s Hospital of Foshan City from January 2016 to March 2019 were selected as the control group.The Mg and CT nucleic acid assays of urinary tract secretions in male NGU patients and healthy subjects in Foshan area were performed by using SAT-RNA detecting technique.The infection rates of Mg and CT in the two groups were compared,and the infection rates of Mg and CT in different age groups in the case group were compared to analyze the relationship between Mg,CT infection and male NGU.Results The detection rates of Mg and CT in the case group were higher than those in the control group,and the differences were statistically significant(P<0.05).The infection rates of Mg and CT in the>30-40 years old group were the highest.No significant differences were observed in the distribution of Mg and CT infection in different age groups(P>0.05).According to Pearson correlation analysis,reproductive tract Mg and CT infection were positively correlated with male NGU(r=0.14,0.16,P<0.05).Conclusion Male NGU is associated with Mg and CT infection,which clinicians should pay attention to.As routine examination items for urinary tract infection,Mg and CT have important clinical significance in the detection of male NGU.