早期识别和评估脓毒性休克的研究进展

Advances in the early Identification and Assessment of Septic Shock

脓毒性休克是脓毒症合并出现的严重循环障碍和细胞代谢紊乱的感染性疾病,有较高病死率,是急危重症医学面临的重要临床问题。目前脓毒性休克的发病率依旧处于升高态势,并且已成为世界范围内病危与死亡的主因,即便患者存活,也会存在长期的认知、心理和生理障碍。早期识别、评估与恰当处理是降低脓毒性休克死亡率的关键。现通过对脓毒性休克的定义、诊断标准、早期临床表现和生物标志物进行综述,为今后此类患者的早期诊断及治疗提供参考,以提高患者生存率,改善患者临床预后。

Septic shock is an infectious disease with severe circulatory disturbance and cell metabolic disorder in sepsis.it has a high mortality rate and is an important clinical problem in critical care medicine.The incidence of septic shock is still on the rise,and has become the leading cause of death and death worldwide.Even if patients survive,there will be long-term cognitive,psychological and physiological disorders.Early identification,evaluation and proper management are the keys to reduce the mortality of septic shock.This article reviews the definition,diagnostic criteria,early clinical manifestations and biomarkers of septic shock in order to provide references for the early diagnosis and treatment of septic shock in order to improve the survival rate and clinical prognosis.