关节镜下软骨下骨钻孔术治疗膝关节软骨损伤的临床效果及对患者膝关节Lysholm评分、炎性因子水平的影响

Clinical effect of arthroscopic subchondral bone drilling in the treatment of knee articular cartilage injury and its influence on knee Lysholm score and inflammatory factor levels

目的探究关节镜下软骨下骨钻孔术治疗膝关节软骨损伤的临床效果及对患者膝关节Lysholm评分、炎性因子水平的影响。方法选取本院2019年1月至12月收治的96例膝关节软骨损伤患者作为研究对象,根据治疗方式将其分为参照组(48例,保守治疗)和研究组(48例,关节镜下软骨下骨钻孔术治疗)。比较两组患者的膝关节Lysholm评分、疗效及炎性因子水平。结果治疗后3个月,两组的膝关节Lysholm各指标评分均高于治疗前,且研究组高于参照组,差异具有统计学意义(P<0.05)。治疗后3个月,研究组的治疗总有效率高于参照组,差异具有统计学意义(P<0.05)。治疗后3个月,两组的IL-6、CRP、TNF-α水平均低于治疗前,IL-10水平高于治疗前,且研究组优于参照组(P<0.05)。结论关节镜下软骨下骨钻孔术治疗膝关节软骨损伤的临床效果显著,可提升患者的膝关节Lysholm评分,有效改善炎性因子水平,值得临床进一步推广和应用。

Objective To explore the clinical effect of arthroscopic subchondral bone drilling in the treatment of knee articular cartilage injury and its influence on knee Lysholm score and inflammatory factor levels.Methods A total of 96 patients with knee articular cartilage injury admitted in our hospital from January to December 2019 were selected as the research objects,the patients were divided into reference group(48 cases,conservative treatment)and study group(48 cases,arthroscopic subchondral bone drilling treatment)according to the treatment method.The knee Lysholm score,efficacy and inflammatory factor levels of the two groups were compared.Results Three months after treatment,the knee Lysholm scores in the two groups were higher than those before treatment,and those in the study group were higher than the reference group,and the differences were statistically significant(P<0.05).Three months after treatment,the total effective rate of treatment in the study group was higher than that in the reference group,and the difference was statistically significant(P<0.05).Three months after treatment,the levels of IL-6,CRP and TNF-α in the two groups were lower than those before treatment,the level of IL-10 was higher than before treatment,and those in the study group were better than the reference group(P<0.05).Conclusion Arthroscopic subchondral bone drilling in the treatment of knee articular cartilage injury has a significant clinical effect,it can improve the patient's knee Lysholm score and effectively ameliorate inflammatory factor levels,which is worthy of further clinical promotion and application.