中国脑卒中后抑郁患病率meta分析

A meta⁃analysis on prevalence of post⁃stroke depression in China

目的通过meta分析了解我国脑卒中后抑郁患者(PSD)患病情况。方法检索知网、万方、维普、PubMed等数据库,收集2021年2月28日前有关中国脑卒中后抑郁患病率相关研究文献。利用Stata 11.0软件进行meta分析。结果共纳入50篇文献,总样本量22822例。meta分析结果显示中国PSD总患病率为34.9%(95%CI:31.7%~38.1%)。亚组分析显示女性患病率高于男性、复发患者患病率高于首发患者,差异均有统计学意义(P<0.05)。不同婚姻状态、受教育程度、年龄、地区、调查年份、卒中类型和卒中部位之间差异没有统计学意义。结论我国卒中后抑郁患者患病率较高,应及早识别卒中后抑郁患者,并进行科学治疗及干预。

Objective To understand the prevalence of post⁃stroke depression in China by using a meta⁃analysis.Methods After searching the databases including CNKI,Wangfang,VIP,and Pubmed,we collected the relevant literature on the prevalence of post⁃stroke depression in China before February 28,2021.The Stata 11.0 software was used for meta⁃analysis.Results A total of 50 articles were included,with a total sample size of 22822 persons.The prevalence of post⁃stroke depression in China was 34.9%(95%CI:3.17%~38.1%).A sub⁃group analysis showed that the prevalence of female was higher than that of male,and the prevalence of recurrent patients was higher than that of incipient patients,the differences were statistically significant(P<0.05).There were no significant differences in marital status,education level,age,residential region,survey year,stroke types and stroke location.Conclusions The prevalence of post⁃stroke depression is higher in China.Clinicians should identify patients with post⁃stroke depression as early as possible,and carry out proper treatment and inter⁃vention.