摘要
血浆基质制品生物活性良好,因其来源于自身,少见不良反应,已被广泛应用于组织再生领域。随着生物医学及材料学的发展,血浆基质制品经历了不同的发展阶段,其制备方式、产物特征、生物学性能都发生了巨大变化。本文通过总结过往研究,系统介绍了血浆基质制品的发展演化历程、理论基础、产物特性及具体成分,并为其在口腔临床中的应用提供参考。
The plasmatrix has good biological activity,it derives from patients′themselves tissues and has no adverse reactions,thus it has been widely used in tissue regeneration.With the development of biomedicine and material science,plasmatrix have gone through different stages of development,their preparation methods,product characteristics and biology have all changed.This article summarizes past research and systematically introduces the development process,theoretical basis and product characteristics of plasmatrix,so as to provide guidance for their application in the process of tissue regeneration.
作者
张玉峰
hang Yufeng(The State Key Laboratory Breeding Base of Basic Science of Stomatology&Key Laboratory of Oral Biomedicine Ministry of Education,School of Stomatology,Wuhan University,Wuhan 430079,China)
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2021年第8期740-746,共7页
Chinese Journal of Stomatology
基金
国家杰出青年科学基金(82025011)。
关键词
富血小板血浆
血浆基质
自体血液提取物
血小板
水平离心
组织再生
Platelet-rich phasma
Plasmatrix
Autologous blood-derived product
Blood platelets
Horizontal centrifugation
Tissue regeneration