LS7综合干预对急性脑梗死预后的影响

Effect of LS7 comprehensive intervention on prognosis of acute cerebral infarction

目的探讨简单7步骤生活指南(LS7)综合干预对急性脑梗死预后的影响。方法将68例急性脑梗死患者均分为对照组和LS7组。对照组予常规治疗、康复训练及其相关疾病治疗,LS7组在对照组基础上进行LS7综合干预。观察两组患者治疗前后LS7评分、BI评分及Morisky服药依从性量表评分、卒中量表评分(NIHSS)、改良Rankin量表评分(mRS)、汉密尔顿焦虑量表评分(HAMA)、汉密尔顿抑郁量表评分(HAMD)。观察两组治疗后的复发情况。结果两组患者治疗后LS7、BI及Morisky服药依从性量表评分较治疗前均明显增高(P<0.05),且LS7组评分高于对照组(P<0.05)。两组患者治疗后NIHSS、mRS、HAMA、HAMD评分较治疗前均明显降低(P<0.05),且LS7组评分均低于对照组(P<0.05)。两组患者复发率比较,差异无统计学意义。结论LS7综合干预可有效降低脑梗死神经功能缺损程度、提高患者服药依从性、降低卒中后焦虑抑郁发生,从而提高患者生存质量。

Aim To explore the effect of life's simple 7(LS7)comprehensive intervention on the prognosis of acute cerebral infarction.Methods 68 patients with acute cerebral infarction were selected and divided into control group and LS7 group.The control group was given conventional antiplatelet therapy,lipid-lowering and plaque stabilizing therapy,rehabilitation training and other related diseases.LS7 group was given LS7 comprehensive intervention.LS7 score,barthel index(BI)score,Morisky medication compliance scale score,national institute of health stroke scale(NIHSS),modified Rankin scale(mRS),hamilton anxiety scale(HAMA)score,hamilton depression scale(HAMD)score were observed before and after treatment.The recurrence of the two groups after treatment was observed.Results After treatment,LS7 score,BI score and Morisky medication compliance scale score in two groups were significantly higher than before treatment(P<0.05),and LS7 group score was higher than control group(P<0.05).After treatment,the NIHSS score,mRS score,HAMA score and HAMD score in two groups were significantly lower than those before treatment(P<0.05),and the scores in LS7 group were lower than those in control group(P<0.05).There was no statistical significance in the recurrence between the two groups.Conclusion LS7 comprehensive intervention can effectively reduce the degree of neurological deficit,improve the medication compliance of patients,reduce the incidence of post-stroke anxiety and depression,and improve the quality of life of patients.