小剂量糖皮质激素吸入治疗支气管哮喘的效果

Effect of Inhaling Small Dose Glucocorticoid to Treat Bronchial Asthma

目的分析小剂量糖皮质激素吸入对支气管哮喘治疗的效果。方法选择72例支气管哮喘患者作为研究对象,病例选取时间在2019年5月—2020年5月,随机分为观察组和对照组,其中观察组通过小剂量糖皮质激素布地奈德吸入治疗,对照组通过常规疗法治疗,对比两组患者的治疗效果、不良反应发生率、肺功能指标以及气道阻力及气道传导率。结果观察组的治疗效果高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。观察组的FEV_(1)、FVC、FEV_(1)\FVC等肺功能指标为(2.89±0.65)L/s、(85.57±6.74)L/s、(87.68±5.07)%,均优于对照组,差异有统计学意义(P<0.05)。观察组治气道阻力及气道传导率为(158.83±19.73)P/V、(86.44±5.92)%,均优于对照组,差异有统计学意义(P<0.05)。结论小剂量糖皮质激素吸入治疗支气管哮喘效果显著。

Objective To analyze the effect of low-dose glucocorticoid inhalation on the treatment of bronchial asthma.Methods 72 patients with bronchial asthma were selected as the research object,and the cases were selected from May 2019 to May 2020.They were randomly divided into an observation group and a control group.The observation group was treated with low-dose glucocorticoid budesonide inhalation.The control group was treated with conventional therapy and compared the treatment effect,incidence of adverse reactions,lung function indexes,airway resistance and airway conductance between the two groups.Results The treatment effect of the observation group was higher than that of the control group,and the incidence of adverse reactions was lower than that of the control group.The contrast was P<0.05,the difference was statistically significant.The FEV_(1),FVC,FEV_(1)\FVC and other pulmonary function indexes of the observation group were(2.89±0.65)L/s,(85.57±6.74)L/s,(87.68±5.07)%,which were better than those of the control group,P<0.05,the difference was statistically significant.The treatment airway resistance and airway conductivity of the observation group were(158.83±19.73)P/V and(86.44±5.92)%,which were better than those of the control group,P<0.05,the difference was statistically significant.Conclusion Low-dose glucocorticoid inhalation is effective in treating bronchial asthma.