识别和预测年龄相关性黄斑变性进展的影像学标志的研究进展

Research progress of imaging markers for identifying and predicting the progression of age-related macular degeneration

随着年龄相关性黄斑变性(age-related macular degeneration,AMD)发病人数的增多,筛选出具有指示价值的影像学标志并应用于AMD的初步筛查、疾病预警、复发提醒、治疗指导,将有助于AMD患者的早期诊断和精准治疗。临床上,大多采用眼底彩照、光学相干断层扫描(optical coherence tomography,OCT)、光学相干断层扫描血管成像(optical coherence tomography angiography,OCTA)和眼底血管造影等进行图像的识别分析。该文综述了识别和预测早、中、晚期AMD进展与预测AMD复发和预后的影像学标志,旨在为临床判断提供理论依据和治疗指导。

With the increase in the number of age-related macular degeneration(AMD)patients,imaging markers with indicative value have been screened and applied to the initial screening of AMD,disease warning,recurrence reminder and treatment guidance to contribute to the early diagnosis and accurate treatment for AMD patients.In clinical practice,colour fundus photography,optical coherence tomography(OCT),optical coherence tomography angiography(OCTA)and fundus angiography are mostly used for image recognition and analysis.This article reviews the imaging markers for identifying and predicting the progression of early-,middle-and late-stage AMD,as well as predicting the recurrence and prognosis of AMD,aiming to provide a theoretical basis and treatment guidance for clinical judgment.