肺部感染控制窗确定序贯通气转换时机在重症肺炎伴呼吸衰竭疗效及预后中的作用

The role of pulmonary infection control window to determine the tim-ing of sequential ventilation in the efficacy and prognosis of severe pneumonia with respiratory failure

目的探讨肺部感染控制窗确定序贯通气转换时机在重症肺炎伴呼吸衰竭患者治疗中的疗效及对其预后的影响。方法选取2017年1月—2019年8月江苏盛泽医院急诊科收治的重症肺炎伴呼吸衰竭的患者80例为研究对象,将患者随机分为观察组与对照组,每组各40例。观察组采用肺部感染控制窗确定序贯通气转换时机,对照组采用传统撤机方法治疗。对比两组患者的疗效及预后情况。结果观察组患者的有创通气时间、机械通气总时间、重症监护病房住院时间、再插管发生率、呼吸机相关肺炎(ventilator associated pneumonia,VAP)发生率明显低于对照组(P<0.05)。两组患者院内死亡率无明显差别(P=0.712)。结论以肺部感染控制窗确定序贯通气转换时机对重症肺炎伴呼吸衰竭患者的疗效及预后中具有积极影响。

Objective To explore the effect of pulmonary infection control window to determine the timing of sequential ventilation in the treatment of patients with severe pneumonia with respiratory failure and its influence on the progno⁃sis.Methods A total of 80 patients with severe pneumonia and respiratory failure admitted to the emergency depart⁃ment of Jiangsu Shengze Hospital from January 2017 to August 2019 were selected as the research objects.The pa⁃tients were divided into an observation group and a control group randomly,with 40 cases in each group.The observa⁃tion group used the pulmonary infection control window to determine the timing of sequential ventilation conversion,and the control group used traditional weaning methods.Compare the efficacy and prognosis of the two groups of pa⁃tients.Results The invasive ventilation time,the total time of mechanical ventilation,the length of stay in the intensive care unit,the incidence of reintubation and the incidence of ventilator associated pneumonia(VAP)in the observation group were significantly lower than those in the control group(P<0.05).There was no significant difference in hospital mortality between the two groups(P=0.712).Conclusion Using the pulmonary infection control window to determine the timing of sequential ventilation has a positive impact on the efficacy and prognosis of patients with severe pneumo⁃nia with respiratory failure.