某三甲医院健康体检人群甲状腺结节检出率及影响因素分析

Analysis of thyroid nodule detection rate and factors among healthy physical examination population in Hefeidistrict

目的通过对健康体检人群甲状腺超声检测结果进行分析,了解某三甲医院健康体检人群甲状腺结节检出情况并分析其影响因素,为指导本地区甲状腺结节防治工作提供依据。方法采用随机号码表抽取样本的方法选取2017年6月至2020年6月于安徽医科大学第一附属医院体检中心体检并行甲状腺彩超检查的18762例体检人群为研究对象,收集研究对象一般资料如年龄、性别、体质量,是否吸烟、饮酒等,并以此分组;同时根据甲状腺超声结果将受试者分为甲状腺结节(TN)组和非甲状腺结节(NTN)组,以分析研究对象的甲状腺结节检出率及其影响因素。结果共筛选出受试者500例,年龄24~90岁,共检出甲状腺结节133例,总检出率为26.6%。男性甲状腺结节检出率(21.0%)低于女性(30.9%),差异有统计学意义(χ^(2)=6.249,P=0.012);40岁~年龄组甲状腺结节检出率(29.7%)最高,20岁~年龄组(18.3%)次之,60~90岁年龄组(6.1%)最低,3个年龄组间甲状腺结节检出率差异有统计学意义(χ^(2)=30.812,P<0.001)。女性(OR=1.687,95%CI:1.117~2.540)、超重(OR=1.565,95%CI:1.039~2.358)是甲状腺结节发生的独立危险因素。结论某三甲医院体检人群中女性甲状腺结节检出率明显高于男性,40~60岁是甲状腺结节发生的高危年龄;性别、超重是影响甲状腺结节发生的独立危险因素。

Objective To understand the detection of thyroid nodules in healthy people in Hefei area by analyzing the results of thyroid ultrasound detection in healthy people,and analyze the related factors affecting the occurrence of thyroid nodules,so as to guide the effective prevention and treatment of thyroid nodules in this area.Methods Random number table method was used to select 500 people who underwent thyroid color Doppler ultrasound and physical examination in the Physical Examination Center of the First Affiliated Hospital of Anhui Medical University from June 2017 to June 2020 as the research objects.The general data of the research objects,such as age,gender,height,weight,smoking,drinking,etc.,were collected and divided into groups.At the same time,according to the results of thyroid ultrasound,the subjects were divided into thyroid nodules(TN)group and non thyroid nodules(NTN)group.Results A total of 500 healthy subjects,aged between 24 and 90 years old,were included in the study.A total of 133 thyroid nodules were detected,with a total detection rate of 26.6%.The detection rate of thyroid nodules in men(21.0%)was lower than that in women(30.9%),and the difference was statistically significant(χ^(2)=6.249,P=0.012).The examination found that the probability of thyroid nodules was the highest among people over 40 years old,accounting for 29.7%,the detection rate was the second among people over 20 years old,accounting for 18.3%,and the detection rate was the lowest among people aged 60~90 years old,accounting for 6.1%.There was significant difference in the detection rate of thyroid nodules among the three age groups(χ^(2)=30.812,P<0.001).Female(OR=1.687,95%CI:1.117~2.540)and over weight(OR=1.565,95%CI:1.039~2.358)were independent risk factors for thyroid nodules.Conclusions The detection rate of thyroid nodules in women is significantly higher than that in men in Hefei area.40-59 years old is the high risk age of thyroid nodules.Gender,overweight/obesity are independent risk factors for thyroid nodules.Therefore,it is of great clinical significance for the early prevention and treatment of thyroid diseases to popularize thyroid color Doppler ultrasound in healthy people,especially middle-aged women.