膈神经传导检测在肌萎缩侧索硬化诊断中的研究进展

Recent advance in detection of phrenic nerve conduction in diagnosis of amyotrophic lateral sclerosis

呼吸衰竭是肌萎缩侧索硬化(ALS)患者的主要死亡原因。膈神经传导检测是客观评估呼吸功能的重要方法,可以弥补肺功能检查(PFT)的局限性,对尽早采取有效措施以提高ALS患者生存质量具有一定的临床价值。本文现围绕膈神经传导的神经生理机制、检测方法及其在ALS中的临床应用展开综述,以提高医务工作者对其的认识,更好地服务临床。

Respiratory failure is the main causes of death in patients with amyotrophic lateral sclerosis(ALS).Detection of phrenic nerve conduction is an important method for objective assessment of respiratory function,which can make up for the limitations of pulmonary function test(PFT),and has a certain clinical value in improving the quality of life of ALS patients by early and effective measures.This article focuses on the neurophysiology and edetection methods of phrenic nerve conduction and its clinical application in ALS to improve the understanding of clinicians and better serve clinic.