药物涂层球囊与药物洗脱支架对冠状动脉支架再狭窄的治疗效果

Comparison of Clinical Outcomes of Drug-coated Balloon and Drug-eluting Stents in the Treatment of In-stent Restenosis

目的探讨药物涂层球囊与药物洗脱支架对冠状动脉支架再狭窄的治疗效果。方法选取2018年2月-2019年3月我院收治的54例冠状动脉支架再狭窄患者,按随机数字表法分为药物涂层球囊组(A组)和药物洗脱支架组(B组)。比较两组靶病变管腔直径面积变化、不良心血管事件、再狭窄及死亡率。结果治疗后B组最小管腔直径、面积优于A组(P<0.05)。两组不良心血管事件发生率无统计学意义(P>0.05)。两组再狭窄率、死亡率无统计学意义(P>0.05)。结论药物洗脱支架相对于药物涂层球囊可在短期内有效改善冠状动脉支架内再狭窄程度,但通过长期随访结果显示两者发生不良心血管事件及再狭窄、死亡情况无显著差异,临床可根据患者情况选择性治疗。

Objective To investigate the clinical effect of drug-coated balloon and drug-eluting stents in the treatment of in-stent restenosis.Methods 54 patients with in-stent restenosis in our hospital from February 2018 to March 2019 were enrolled,and divided into two groups by random number table methods.Group A received drug-coated balloon,and group B received drug-eluting stents.The changes of diameter and area of lumen,and incidence rate of restenosis and mortality rate were compared between groups.Results After treatment,the smallest lumen diameter and area of group B were better than those of group A(P<0.05).The incidence of adverse cardiovascular events had significant difference between groups(P>0.05).The restenosis rate and mortality rate of had no significant difference between groups(P>0.05).Conclusion Compared with drug-coated balloon,drug-eluting stents can significantly ameliorate the restenosis in short term,and the long-term results show no significant difference in cardiovascular events,restenosis,and mortality rate between two methods,so clinical application can be determined based on patients’conditions.