马堃教授以肾虚血瘀论治高泌乳素血症所致不孕病案举隅

Examples of Professor MA Kun′s treatment of infertility caused by hyperprolactinemia with kidney deficiency and blood stasis

该文探讨马堃教授以肾虚血瘀论治高泌乳素血症导致排卵障碍性不孕的理论依据及组方原则。中医理论"肾-天癸-冲任-胞宫轴"为主导女性生殖生理功能的根基,其中肾为最关键的一环:肾主生殖,充沛的肾阴肾阳是肾-天癸-冲任-胞宫轴的物质基础和能量来源。马堃教授认为肾虚能够直接促使高泌乳素血症导致的不孕症,肾虚血瘀是高泌乳素血症导致排卵障碍性不孕的发病基础。作为病理结果,血瘀在其发病的过程贯穿始终,亦是高泌乳素血症病程进展的促成因素。在此基础上,马堃教授以补肾活血法为治疗高泌乳素血症导致排卵障碍性不孕的原则,根据月经周期气血变化规律和卵泡生长过程,滋肾阴,温肾阳,阴阳同补,兼以活血化瘀、疏肝理气,组成补肾促卵方,并随症加减治疗高泌乳素血症导致的排卵障碍性不孕,效果显著。该文举例补肾促卵方成功治疗高泌乳素血症导致不孕病案,验证马堃教授以肾虚血瘀论治高泌乳素血症导致不孕的可行性和有效性,可供广大中医妇科医务工作者参考、借鉴。

Hyperprolactinemia(HPRL) is one of the diseases leading to anovulatory infertility, which is a refractory gynecological disease and seriously affects female reproductive function. Professor MA Kun has summarized his experience in clinical and scientific studies for many years. And believes that kidney deficiency is the pathogenesis of HPRL and blood stasis is the dominant pathological manifestation of HPRL and can promote the progress of the disease. In view of this, Professor MA Kun took the therapy of kidney-tonifying and blood-activating as the principle for treating anovulatory infertility caused by HPRL, with soothing the liver and promoting Qi as adjuvant therapies. She has also summarized and refined the prescriptions for tonifying kidney and inducing ovulation, which have a remarkable clinical efficacy.