摘要
目的临床分析三种肿瘤标志物与HPV联合检测在宫颈癌早期筛查中的应用效果。方法采用回顾性方法分析,选取本院自2020年1月至2020年6月就诊及体检人员共104人,把所有病例分为健康查体组、宫颈癌前病变组和宫颈癌三组进行比较分析。对以上病例行HPV和SCCA、CA125、CYFRA21-1三种肿瘤标志物检查。分析三种肿瘤标志物与HPV联合检测在宫颈癌早期筛查中的应用价值。结果与健康体检组、宫颈癌前病变组相比,宫颈癌组患者的SCCA、CYFRA21-1、CA125水平更高,差异具有统计学意义(P<0.05)。与单一检测相比,SCCA+CYFRA21-1+CA125+HPV检测的阳性率更高,差异具有统计学意义(P<0.05)。结论宫颈癌早期筛查中采用三种肿瘤标志物与HPV联合检测有着较高的应用价值,值得临床应用。
Objective:To analyze the application effect of three tumor markers combined with HPV in early screening of cervical cancer.Methods:From January 2020 to June 2020,a total of 104 people were selected.All cases were divided into three groups:health examination group,cervical precancerous lesion group and cervical cancer group.HPV and SCCA,CA125,CYFRA21-1 were detected in the above cases.The application value of combined detection of three tumor markers and HPV in clinical diagnosis was analyzed.Results:The levels of SCCA,CYFRA21-1 and CA125 in cervical cancer group were higher than those in health examination group and cervical precancerous lesion group(P<0.05).Compared with single detection,the positive rate of SCCA+CYFRA21-1+CA125+HPV detection was higher,and the difference was statistically significant(P<0.05).Conclusion:The combined detection of three tumor markers and HPV in early screening of cervical cancer has high application value,which is worthy of clinical application.
作者
乔小霞
崔建健
Qiao Xiaoxia;Cui Jianjian(Ningxia Hospital of Traditional Chinese Medicine and Research Institute of Traditional Chinese Medicine, Yinchuan Ningxia, 750021, China)
出处
《中外女性健康研究》
2021年第14期1-2,181,共3页
Women＇s Health Research
基金
宁夏医科大学科学研究基金资助项目,课题名称:三种肿瘤标志物与HPV联合检测在宫颈癌早期筛查中的应用,课题编号:XM2019138。
