广州市大气气态污染物与儿童支气管肺炎住院关系的时间序列研究

Time series study on the relationship between air gaseous contaminants children with bronchopneumonia in Guangzhou

目的探讨大气气态污染物与儿童支气管肺炎住院的关系。方法收集2015年1月至2019年12月期间,广州市的一氧化碳(CO)、二氧化氮(NO_(2))、二氧化硫(SO_(2))和臭氧(O_(3))等大气气态污染物日平均浓度和气象条件(包括日平均气温和相对湿度)、因支气管肺炎住院患儿等数据,采用广义相加模型分析上述气态污染物与儿童支气管肺炎入院人数的关系。结果研究发现,2015-2019年期间,广州市CO日均浓度每升高1 mg/m^(3),儿童支气管肺炎入院人数增加4.16倍(95%CI:1.49,6.90);NO_(2)、SO_(2)浓度每升高10μg/m^(3),儿童支气管肺炎入院人数分别增加8.13倍(95%CI:1.91,14.74)、2.17倍(95%CI:0.83,3.53)。结论CO、NO_(2)、SO_(2)日平均浓度的升高可能与儿童发生支气管肺炎住院风险的上升有关。

Objective To investigate the relationship between atmospheric gas pollutants and bronchial pneumonia in children.Methods Collection from January 2015 to December 2019,Guangzhou City,Carbon monoxide(CO),nitrogen dioxide(NO_(2)),sulfur dioxide(SO_(2))and the ozone(O_(3))Data from the daily average concentration of atmospheric gas pollutants,meteorological conditions(including the daily average temperature and relative humidity),and children hospitalized due to bronchial pneumonia,The relationship between the number of bronchial pneumonia in children was analyzed by a generalized additive model.Results 2015-2019,Every daily concentration of CO in Guangzhou 4.16 times(95%CI:1.49,6.90);NO_(2)、SO_(2) concentration per 10μg/m^(3),increase 8.13 times(95%CI:1.91,14.74),2.17 times(95%CI:0.83,3.53).Conclusion The daily average CO、NO_(2)、SO_(2) may be associated with the increased risk of bronchial pneumonia in children.