老年舒张性心力衰竭合并肌少症病人的临床特征

Clinical characteristics of elderly patients with diastolic heart failure complicated with sarcopenia

目的探讨老年舒张性心力衰竭(DHF)合并肌少症病人的临床特征,分析肌少症对DHF病人躯体活动能力的影响。方法纳入符合条件的住院病人120例,分为肌少症组和非肌少症组,比较2组一般临床资料、骨骼肌质量指数(SMI)、握力、4 m步行速度,以步速<0.8 m/s定义为躯体活动能力降低。采用Logistic回归分析躯体活动能力下降的危险因素。结果DHF病人中54.17%合并肌少症。和非肌少症组对比,肌少症组的BMI、TG、SMI、握力、4 m步行速度明显降低,年龄偏大(P<0.05)。Logistic回归分析显示,年龄、脑梗死、SMI是躯体活动能力下降的独立影响因素。结论肌少症是老年DHF病人常见的合并症,年龄、脑梗死、SMI均会影响病人躯体活动能力,从而影响其生存质量。

Objective To investigate the clinical characteristics of the elderly patients with diastolic heart failure(DHF)complicated with sarcopenia,and to analyze the effect of sarcopenia on physical activity.Methods A total of 120 eligible inpatients were included and divided into the sarcopenia group(n=65)and the non-sarcopenia group(n=55).The general clinical data,skeletal muscle mass index(SMI),grip strength,walking speed of 4 m in two groups were compared.Physical acticity decreasing was identified as 4 m walking speed less than 0.8 m/s.Logistic regression analysis was used to analyze the risk factors of physical activity decreasing.Results In the DHF patients,54.17%patients were complicated with sarcopenia.Compared with the non-sarcopenic group,the body mass index(BMI),tridlyceride(TG),SMI,grip strength and the walking speed of 4 m in the sarcopenia group were significantly decreased,and the age was older(P<0.05).Logistic regression analysis showed that the age,cerebral infarction and SMI were independent influencing factors for decreased physical activity.Conclusions Sarcopenia is a common complication in DHF patients.Age,cerebral infarction and SMI will influence the patients’physical activity ability,thus affecting their quality of life.