Peripheral Blood Mitochondrial DNA Copy Number and Hypertension Combined with Albuminuria in Chinese Coal Miners

Hypertension is an increasingly prevalent chronic disease that affects approximately 1 billion people worldwide.Elevated blood pressure inflicts longterm damage to various organs,including the kidneys.Hypertension aggravates the clinical course of chronic kidney disease,and promotes progression toward end-stage renal disease.Among the cases of end-stage renal disease,30%are directly attributable to hypertension.Though the molecular mechanism responsible for renal injury remains largely unknown,elucidating this mechanism is critical to preventing these deleterious complications.