米氮平联合艾司唑仑治疗女性失眠症的临床疗效观察

Study on the Efficacy of Mirtazapine Combined with Estazolam in the Treatment of Female Insomnia

目的:研究米氮平联合艾司唑仑治疗女性失眠症的临床疗效。方法:选取2018年5月至2020年5月无锡市人民医院收治的女性失眠症患者100例作为研究对象,随机分为观察组和对照组,每组50例。对照组采用艾司唑仑治疗,观察组采用米氮平联合艾司唑仑治疗,比较2组治疗效果和睡眠质量(PSQI)评分。结果:观察组的治疗有效率为98%,明显高于对照组的72%,且观察组患者治疗后的PSQI评分改善情况优于对照组,差异均有统计学意义(均P<0.05)。结论:米氮平联合艾司唑仑治疗女性失眠症疗效可靠,可明显改善患者的睡眠质量,值得临床推广应用。

Objective:To study the clinical efficacy of mirtazapine combined with estazolam in the treatment of female insomnia.Methods:A total of 100 female insomniac patients admitted to Wuxi People′s Hospital from May 2018 to May 2020 were randomly divided into observation group(mirtazapine combined with esazolam)and control group(esazolam),with 50 cases in each group.The treatment effect and sleep quality were compared between the two groups.Results:The effective rate of the observation group was 98%,which was higher than that of the control group(72%).The improvement of PSQI scores in the observation group was better than that in the control group after treatment,with statistical significance(P<0.05).Conclusion:Mirtazapine combined with estazolam is effective in the treatment of female insomnia and can significantly improve the sleep quality of patients,it is worthy of clinical application.