洛赛克联合西沙比利治疗反流性食管炎42例临床观察

Clinical Observation on 42 Cases of Reflux Esophagitis Treated with Losec and Cisapride

目的分析应用洛赛克联合西沙比利对反流性食管炎进行治疗的效果。方法将2018年4月至2019年4月来我院进行治疗的42例反流性食管炎患者作为观察组,选择同期另外42例反流性食管炎患者作为本文对照组,分别对两组患者通过洛赛克联合西沙比利和单纯的西沙比利治疗,比较不同治疗的效果。结果观察组治疗总有效率为95.24%(40/42),对照组治疗有效率为76.19%(32/42),P<0.05;观察组的并发症发生率为7.14%(3/42),对照组并发症发生率为23.81%(10/42),P<0.05;比较两组患者在治疗结束后的WHOQL-100量表评分和症状积分方面的差异,观察组都明显比对照组更优,P<0.05。结论临床对反流性食管炎患者治疗时选择洛赛克联合西沙比利治疗可以有效提升整体治疗的总有效率,并且不会产生严重的并发症,可有效改善患者的临床症状。

Objective To analyze the effect of Losec combined with cisapride on reflux esophagitis.Methods 42 patients with reflux esophagitis who came to our hospital from April 2018 to April 2019 were enrolled in the study.Another 42 patients with reflux esophagitis were selected as the control group in the same period.The effects of different treatments were compared by Losec combined with cisapride and simple cisapride.Results The total effective rate was 95.24%(40/42)in the observation group,76.19%(32/42)in the control group,P<0.05.The complication rate in the observation group was 7.14%(3/42).The complication rate of the control group was 23.81%(10/42),P<0.05.The differences between the two groups in the WHOQL-100 scale score and symptom score after treatment were compared,the observation group was significantly better than the control group,P<0.05,there is statistical significance.Conclusion The choice of Losec plus cisapride in the treatment of patients with reflux esophagitis can effectively improve the overall efficiency of the overall treatment,and will not cause serious complications,which can effectively improve the clinical symptoms of patients.