重视非肝硬化门脉高压症的早期诊断

Early diagnosis of non-cirrhotic portal hypertension should be taken seriously

非肝硬化门脉高压症(NCPH)是指在没有肝硬化或不完全间隔性肝硬化(ISC)患者,门静脉压力梯度明显升高,而肝静脉压力梯度正常或轻度升高,以肝脏血管病变为特征,临床表现为门脉高压症、病因复杂的一组异质性疾病。其命名尚未完全统一。相同病因所致的NCPH,在不同阶段其肝脏病理及临床表现不同。食管胃静脉曲张出血是NCPH最常见的并发症,容易漏诊或误诊为肝硬化。NCPH病因治疗是关键,内镜及药物是治疗NCPH并发食管胃静脉曲张出血的有效方法。

Non-cirrhotic portal hypertension(NCPH)refers to a group of heterogeneous diseases with the clinicalmanifestations of portal hypertension and complex etiology,and characterized by significantly elevated portal pressure gradient,normal or slightly elevated hepatic vein pressure gradient and hepatic vascular lesions in patients without cirrhosis or incomplete septal cirrhosis(ISC).The nomenclature has not yet been fully unified.The hepatic pathology and clinical manifestations of NCPH caused by the same etiology are different in different stages.Esophagogastric variceal bleeding is the most common complication of NCPH,which is easy to be missed or misdiagnosed as liver cirrhosis.Aiming at the etiology is the key to the successful treatment of NCPH.Endoscopy and drugs are effective methods for thetreatment of NCPH complicated with esophagogastric variceal bleeding.