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引药入肺兼扶正自拟方治疗甲状腺结节临床观察 被引量:2

Clinical Observation on the Treatment of Thyroid Nodules by Introducing Medicine into the Lung with Self-made Prescription for Strengthening Body Resistance
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摘要 目的观察引药入肺兼扶正自拟方治疗良性甲状腺结节的临床疗效。方法选择良性甲状腺结节患者80例,采用非随机对照研究,根据患者意愿按就诊次序分为观察组及对照组,每组各40例。对照组患者口服小剂量左甲状腺钠片治疗,观察组患者服用引药入肺兼扶正自拟方,12周为1个疗程,连服2个疗程随访。结果观察组在经过治疗后,其临床总有效率为70%,显著高于对照组的20%,差异有统计学意义(P<0.05);观察组治疗后,中医症状总积分较治疗前显著下降(P<0.05),对照组总积分改善不明显,差异无统计学意义(P>0.05),2组间比较,差异有统计学意义(P<0.05);观察组治疗后最大结节直径较治疗前缩小(P<0.05),而对照组无明显变化(P>0.05),且观察组直径小于对照组(P<0.05);2组治疗后肝肾功能、血常规均无异常,也未发生胃肠道等不良反应。结论引药入肺兼扶正自拟方治疗良性甲状腺结节安全有效,值得临床推广。 Objective:To observe the clinical effect of introducing medicine into the lung with self-made prescription for strengthening body resistance in treating benign thyroid nodules.Methods:80 patients with benign thyroid nodules were selected and a non-randomized controlled study was adopted.According to the wishes of the patients,they were divided into an observation group and a control group,40 cases per group.The patients in the control group were treated with low-dose left thyroid sodium tablets and the patients in the observation group were treated with the introduction of the medicine into the lung and the self-made prescription for strengthening body resistance.12 weeks was a course of treatment and the patients were followed up 2 courses later.Results:After treatment,the total clinical effective rate of the observation group was 70%,which was significantly higher than 20% of the control group.The difference was statistically significant(P<0.05).After treatment,the total score of TCM symptoms of the observation group decreased significantly than the prior treatment(P<0.05),but the total score of the control group did not improve significantly,and the difference was not statistically significant(P>0.05).The difference between the two groups was statistically significant(P<0.05).The largest nodule in the observation group reduced after treatment and the diameter was smaller than the prior treatment(P<0.05),while the control group had no significant change(P>0.05).The observation group had a smaller diameter than the control group(P<0.05)and there was no abnormality in liver and kidney function and blood routine in the two groups after treatment and also no adverse reactions such as gastrointestinal tract.Conclusion:The introduction of the medicine into the lungs with the self-made prescription for strengthening body resistance is safe and effective for the treatment of benign thyroid nodules and worthy of clinical application.
作者 王柔钧 朱燕 WANG Rou-jun;ZHU Yan(Traditional Chinese Medicine Hospital of Kunming City,Kunming 650011,China)
机构地区 昆明市中医医院
出处 《云南中医中药杂志》 2021年第8期41-44,共4页 Yunnan Journal of Traditional Chinese Medicine and Materia Medica
基金 昆明市科技计划项目(2019-1-S-25318000001517)。
关键词 良性甲状腺结节 引药入肺兼扶正自拟方 临床研究 Benign Thyroid Nodules Introducing Medicine into the Lung with Self-Made Prescription for Strengthening Body Resistance Clinical Research
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