采用胰岛素泵强化治疗2型糖尿病患者的临床疗效分析

Analysis of Clinical Efficacy of Intensive Treatment of Type 2 Diabetes with Insulin Pump

目的探究胰岛素泵强化治疗2型糖尿病患者的临床疗效分析。方法择取2019年1月—2021年1月在该院进行糖尿病治疗的102例患者作为研究对象。就基于对象自主自愿原则予以分组,均分为对照组(51例)与观察组(51例)。对照组予以常规胰岛素注射方式或联合口服药物治疗,观察组则实施胰岛素泵强化治疗方式。分析对比两组对象血糖水平、胰岛素使用剂量、血糖达标时间及低血糖发生频率等情况。结果治疗前,两组空腹血糖水平及餐后2 h血糖水平对比差异无统计学意义(P>0.05);治疗后,观察组空腹血糖水平(6.19±0.52)mmol/L及餐后2 h血糖水平(7.21±0.55)mmol/L优于对照组的(7.55±0.52)、(9.15±0.55)mmol/L,差异有统计学意义(t=18.681、25.195,P=0.002、0.001);观察组血糖达标时间(3.48±0.65)d、胰岛素使用量(34.31±1.54)U/d及低血糖发生频率(1.22±0.45)次/例优于对照组的(6.32±0.65)d、(46.29±1.54)U/d、(3.48±0.45)次/例,差异有统计学意义(t=31.209、55.463、35.873,P<0.05)。结论经胰岛素泵强化治疗2型糖尿病患者效果显著,能有效降低患者空腹血糖浓度,控制血糖水平,降低胰岛素使用剂量,其经济效益和治疗效果均有明显优势。

Objective To explore the clinical efficacy analysis of insulin pump intensive treatment of type 2 diabetes patients.Methods The sample collection time zone was selected from January 2019 to January 2021,and 102 patients who were treated for diabetes in the hospital in this time zone were selected as the research sample objects.The subjects were divided into groups based on the principle of autonomy and voluntariness,and were divided into control group(51 cases)and observation group(51 cases).The control group received conventional insulin injection or combined oral medication;the observation group received intensive insulin pump treatment.Analyze and compare the two groups of subjects'blood glucose levels,insulin dosage,time to reach the target blood glucose,and frequency of hypoglycemia.Results Before treatment,there was no statistically significant difference in the fasting blood glucose level and the blood glucose level 2 h after the meal between the two groups(P>0.05);after treatment,the fasting blood glucose level of the observation group(6.19±0.52)mmol/L and the blood glucose level 2 h after the meal(7.21±0.55)mmol/L was better than the control group's(7.55±0.52)mmol/L and(9.15±0.55)mmol/L,the difference was statistically significant(t=18.681,25.195,P=0.002,0.001);the observation group's blood glucose compliance time(3.48±0.65)d,insulin usage(34.31±1.54)U/d and frequency of hypoglycemia(1.22±0.45)times/case were better than the control group(6.32±0.65)d,(46.29±1.54)U/d,(3.48±0.45)times/case,the difference was statistically significant(t=31.209,55.463,35.873,P<0.05).Conclusion Intensive treatment of type 2 diabetic patients with insulin pump is effective.It can effectively reduce fasting blood glucose concentration,control blood glucose level,and reduce insulin dosage.Its economic benefits and therapeutic effects have obvious advantages and are worthy of further promotion.