膳食和生活方式等对银屑病影响的研究进展

Research Progress of Effect of Diet and Lifestyle on Psoriasis

银屑病是一种免疫介导的慢性炎症性皮肤病,又是一种可伴有关节等受累的多系统疾病,严重影响患者的生理心理健康,近年包括生物制剂在内的治疗能够极大改善患者病情,提高患者生活质量,但多数患者需要维持治疗,且复发率较高。饮食和生活方式与发病及病情严重程度是否相关是患者关心的问题,也是皮肤科医生关注的研究领域。本文通过综合分析近年国内外的研究进展,对银屑病及银屑病关节炎患者的饮食结构和吸烟、饮酒、运动、洗浴等生活方式的研究成果进行综述,相关建议将有助于指导银屑病患者及临床医生采取合理的干预进行疾病管理。

Psoriasis is not only an immune-mediated chronic inflammatory skin disease,but also a multi-system disease in which joints and other tissues could be involved,seriously affecting the physiological and psychological health of patients.In recent years,the treatment methods including biological agents greatly improve patients'symptoms and quality of life,but most patients need maintenance treatment,and the recurrence rate is still high.Whether diet and lifestyle are related to the onset and severity of the disease is the concern of patients,and is also the research focus of dermatologists.Based on the comprehensive analysis of the research progress at home and abroad in recent years,this paper reviews the research results of the diet structure and lifestyle of patients with psoriasis and psoriatic arthritis,such as smoking,drinking,exercise,and bathing.Relevant recommendations will be helpful to guide psoriasis patients and clinicians to take reasonable intervention for disease management.