医药代表收集药品不良反应信息的调查分析

Investigation and Analysis of Medical Representative Collecting the Information of Adverse Drug Reactions

目的:了解目前医药代表进行药品不良反应(ADR)信息收集情况,完善我国ADR信息收集上报制度,保障人民群众用药安全。方法:以随机抽样的方式,对江苏、浙江和广东等地部分企业医药代表进行自填式问卷调查,内容涉及医药代表自身基本信息、学习与工作情况、ADR关注情况等,采用频数及构成比描述调查结果,影响因素分析采用χ2检验、Logistic回归分析。结果:共调查477人,回收有效问卷430份,有效回收率为90.15%,53.00%的受访者为女性,年龄以30岁以上为主,从业年限多在5年以上,70.20%曾就读于医药相关专业。多因素分析结果显示,学历、医药相关专业与国家药品不良反应监测中心年度报告阅读情况等为医药代表收集ADR信息的主要影响因素,结果差异有统计学意义(P<0.05)。结论:现今完全由医药代表进行ADR信息收集上报尚存在许多障碍,但在未来医药代表或可成为ADR信息收集上报的主要责任人。

Objective:To understand the current situation of medical representatives collecting information on adverse drug reactions,to improve the collection and reporting system of the information of adverse drug reaction in our country to ensure the safety of people’s medication.Methods:A self-administered questionnaire survey was conducted among medical representatives of some enterprises in Jiangsu,Zhejiang and Guangdong Province by random sampling.The content was designed for medical representatives’basic information,study and work conditions,the attention and collection of adverse reaction information,the frequency and composition ratio are used to describe the survey results,and the analysis of influencing factors were used byχ2 test and Logistic regression analysis.Results:A total of 477 people were surveyed and 430 valid questionnaires were returned.The effective response rate was 90.15%.53.00%of the respondents were women,mostly aged 30 years or older,with more than 5 years of experience,and 70.20%had studied medicine profession.The analysis of multiple factors showed that academic qualifications,medicine-related majors and reading of the annual report of the National Adverse Drug Reaction Monitoring Center were the main factors of influence medical representative collecting information on adverse drug reaction.The results were significantly different and statistically significant(P<0.05).Conclusion:There are still many obstacles to the collection and reporting of adverse drug reaction information by medical representatives.However,medical representatives may become the main person responsible for the collection and reporting of adverse drug reaction information in the future.