风湿免疫性疾病脉络膜厚度变化的研究进展

Research progress of choroidal thickness in rheumatic immune diseases

风湿免疫性疾病是一组反复发作的全身性疾病,通过炎症因子累及血管系统。眼部反应可作为风湿免疫性疾病免疫再激活或者疾病加重的标志,也可作为风湿免疫性疾病的全身首发表现。脉络膜作为眼部血流最丰富的部位,受全身血管疾病影响较大,脉络膜厚度是眼部受累的极好评价指标。而且光学相干断层扫描技术为观察脉络膜厚度提供了科学准确的测量工具。脉络膜厚度的变化是否可作为风湿免疫性疾病活动、发展或转归的标记,还需要进行更多的研究。本文回顾相关文献,对风湿免疫性疾病脉络膜厚度的变化做一综述。

Rheumatic immune disease,as a group of recurrent systemic diseases,involves the vascular system through inflammatory factors.Eye reaction can be used as a sign of rheumatic immune reactivation or disease aggravation,together with the first systemic manifestation of rheumatic immune disease.As a part of the most abundant blood flow in the eyes,choroid is an excellent evaluation index for ocular involvement,and it is greatly affected by systemic vascular diseases.And optical coherence tomography provides a scientific and accurate measuring tool for the observation of choroid thickness.However,whether changes in choroid thickness can be utilized as markers of disease activity,and progression,our results require further research.In this paper,the changes of choroid thickness in rheumatic immune diseases are analyzed.