维持性血液透析患者认知衰弱的现状及影响因素分析

Analysis on current status and influencing factors of cognitive frailty in Maintenance Hemodialysis patients

目的:调查维持性血液透析患者认知衰弱现状,并分析其影响因素。方法:选取连云港市3所医院共452例维持性血液透析患者为研究对象,采用衰弱表型、简易精神状态检查量表及临床痴呆评定量表进行认知衰弱的筛查,收集相关临床资料,并分析患者认知衰弱的影响因素。结果:93例(20.6%)患者存在认知衰弱,Logistic回归分析结果显示,高龄、女性、腰围较大、存在营养不良风险和抑郁是认知衰弱的危险因素,较高的文化程度和血清肌酐水平是认知衰弱的保护因素(P<0.05)。结论:维持性血液透析患者认知衰弱的发生率较高,医护人员应加强对该人群的关注,及早识别并采取针对性的干预措施。

Objective:To investigate the prevalence of cognitive frailty in Maintenance Hemodialysis patients and to analyze the influencing factors.Methods:A total of 452 Maintenance Hemodialysis patients in 3 hospitals of Lianyungang were selected as the study subjects.The Frailty Phenotype,Mini-Mental State Examination and Clinical Dementia Rating were used to screen for cognitive frailty.The relevant clinical data were collected,and the influencing factors of cognitive frailty were analyzed.Results:Ninety-three patients(20.6%)had cognitive frailty.Logistic regression analysis showed that advanced age,female,larger waist circumference,malnutrition and depression were risk factors for cognitive frailty.Higher education level and serum creatinine level were protective factors for cognitive frailty(P<0.05).Conclusion:The prevalence of cognitive frailty in Maintenance Hemodialysis patients is high.Medical staff should pay more attention to this population,identify early and take targeted intervention.