改性黄腐酸/凹凸棒石复合材料的制备及其抑菌性能

Prepration of Modified Fulvic Acid/Attapulgite Composites and Their Antimicrobial Properties

黄腐酸(FA)具有抑菌消炎和促进动物生长的功效。为了进一步提升FA的广谱抑菌性,以凹凸棒石(APT)为载体,通过吸附法将FA负载于APT,同时进行十六烷基三甲基溴化铵(CTAB)改性。结果表明,FA和APT主要以静电吸附形式结合,CTAB的引入实现了FA/APT复合材料的电荷调控。复合材料对大肠杆菌和金黄色葡萄球菌的最小抑菌浓度(MIC)随着CTAB添加量的增加而减小;当CTAB添加量为15%(质量分数)时,其对大肠杆菌的MIC为1 mg/mL,对金黄色葡萄球菌的MIC为0.05 mg/mL。

Fulvic acid(FA)has the effect of inhibiting bacteria,anti-inflammation,and promoting animal growth.In order to further improve the broad-spectrum antimicrobial properties of FA,a composite was prepared by loading FA into attapulgite(APT)through the adsorption method,meanwhile cetyltrimethylammonium bromide(CTAB)was used to modify the composite.The results show that FA and APT are mainly combined by electrostatic adsorption,and the introduction of CTAB regulates the charge of FA/APT composites.The minimum inhibitory concentration(MIC)of the composites against Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)decreases with the increase of CTAB amount.When the amount of CTAB is 15%(mass fraction),the MIC is 1 mg/mL for E.coli and the MIC is 0.05 mg/mL for S.aureus.